When it comes to healthcare-associated infections (HAIs), central line-associated bloodstream infections (CLABSIs) are among the most critical indicators monitored in hospitals worldwide. However, a growing body of evidence suggests that tracking CLABSIs alone may not provide a comprehensive picture of patient safety and infection control practices. This is where hospital-onset bloodstream infection (HOBSI) tracking comes in: By expanding the scope beyond CLABSIs, HOBSI tracking offers a more holistic and accurate view of bloodstream infections within healthcare facilities. Let’s explore why HOBSI tracking is superior to CLABSI tracking alone.