Objective: Penetrating injuries in the maxillofacial region pose a great challenge due tothe anatomical complexity inherent to the area compounded with vital functions suchas vision and airway. This paper highlights the importance of meticulous preoperativeplanning and a concerted effort of a multidisciplinary team in managing penetratingmaxillofacial injuries.Case Presentation: A 38-year -old man reported to the emergency department with aknife impacted in the medial wall of the orbit, travelling up to the base of the cranium. ACT scan aided in evaluating the site, depth, and relation of the foreign body to the adjacentstructures. A team of oral and maxillofacial surgeons, ENT and neurosurgeon successfullyretrieved the knife and the patient recovered with no morbidities.Conclusions: Penetrating injuries in the maxillofacial region are rare and there is a dearthof documentation in literature. A quick response with proper preoperative planning and ateam approach is paramount in the successful management of these patients.